Volume 2 Fitness Landscape, Red Queen, Evolutionary Enigmas, and Applications to Virology

Igor M. Rouzine

Published by De Gruyter 2023

Volume 2 Fitness Landscape, Red Queen, Evolutionary Enigmas, and Applications to Virology

Igor M. Rouzine

Part of the multi-volume work Mathematical Modeling of Evolution

Volume 8/2 in the series De Gruyter Series in Mathematics and Life Sciences

https://doi.org/10.1515/9783110697384

Overview
Contents

About this book

This two-volume work focuses on the mathematical aspects of Darwinian evolution starting from the basic model of stochastic evolution of a single isolated locus in the presence of mutation to the multi–locus models of sexual and asexual populations. Volume 2 discusses the inference of fi tness landscape from DNA sequence data, discovery of the evolutionary roles of enygmatic traits, co-evolution of adversarial species, and various applications to virus evolution.

Applications to real-life problems for HIV, influenza, and polio virus.
Inference of fitness landscape from genomic data, against the noisy background of linkage.
The evolutionary puzzles of HIV latency and progression to AIDS.

Author / Editor information

Igor M. Rouzine, Russian Academy of Sciences, Russian Federation.

Topics

Frontmatter Publicly Available Download PDF	I
Preface Publicly Available Download PDF	V
Contents Publicly Available Download PDF	VII
Chapter 1 Inference of the acting factors of evolution and basic evolutionary parameters from sequence data Requires Authentication Unlicensed Licensed Download PDF	1
Chapter 2 Inference of fitness landscape from sequence data Requires Authentication Unlicensed Licensed Download PDF	44
Chapter 3 Evolutionary role of a trait Requires Authentication Unlicensed Licensed Download PDF	116
Chapter 4 Evolutionary escape from an opposing species (Red Queen effect) Requires Authentication Unlicensed Licensed Download PDF	181
References Requires Authentication Unlicensed Licensed Download PDF	279
Index Requires Authentication Unlicensed Licensed Download PDF	303

(Deutsch)

Language: English
Publisher: De Gruyter
Audience: Researchers and advanced students in applied mathematics, biophysics, computational biology, complex systems.
Pages
- Front matter: 13
- Main content: 305
Illustrations
- Illustrations: 66
- Coloured Illustrations: 13
- Tables: 19
Keywords: Viruses; Mathematical Modelling; Genealogy; Evolution

eBook

Published: September 18, 2023
ISBN: 9783110697384

Hardcover

Published: September 18, 2023
ISBN: 9783110697315